Choroid plexus papilloma

Atypical choroid plexus papilloma

Choroid plexus carcinoma

Schwannoma

Neurofibroma

Perineurioma

Hybrid nerve sheath tumors

Malignant melanotic nerve sheath tumor

Malignant peripheral nerve sheath tumor

Cauda equina neuroendocrine tumor (previously paraganglioma)

Medulloblastoma

Medulloblastomas, molecularly defined

Medulloblastoma, WNT-activated

Medulloblastoma, SHH-activated and TP53-wildtype

Medulloblastoma, SHH-activated and TP53-mutant

Medulloblastoma, non-WNT/non-SHH

Medulloblastomas, histologically defined

Medulloblastoma, histologically defined

Other CNS embryonal tumors

Atypical teratoid/rhabdoid tumor

Cribriform neuroepithelial tumor

Embryonal tumor with multilayered rosettes

CNS neuroblastoma, FOXR2-activated

CNS tumor with BCOR internal tandem duplication

CNS embryonal tumor NEC/NOS

Neurofibromatosis type 1

Neurofibromatosis type 2

Schwannomatosis

Von Hippel-Lindau syndrome

Tuberous sclerosis

Li-Fraumeni syndrome

Cowden syndrome

Constitutional mismatch repair deficiency syndrome

Familial adenomatous polyposis 1

Nevoid basal cell carcinoma syndrome

Rhabdoid tumor predisposition syndrome

Carney complex

DICER1 syndrome

Familial paraganglioma syndromes

Melanoma-astrocytoma syndrome

Familial retinoblastoma

BAP1 tumor predisposition syndrome

Fanconi anemia

ELP1-medulloblastoma syndrome

Germ cell tumors of the CNS

Adult-type diffuse gliomas

Astrocytoma, IDH-mutant

Oligodendroglioma, IDH-mutant and 1p/19q codeleted

Glioblastoma, IDH-wildtype

Pediatric type diffuse low-grade gliomas

Diffuse astrocytoma, MYB- or MYBL1-altered

Angiocentric glioma

Polymorphous low-grade neuroepithelial tumor of the young

Diffuse low-grade glioma, MAPK pathway-altered

Pediatric-type diffuse high-grade gliomas

Diffuse midline glioma, H3 K27-altered

Diffuse hemispheric glioma, H3 G34-mutant

Diffuse pediatric type high grade glioma, H3-wildtype and IDH-wildtype

Infant-type hemispheric glioma

Circumscribed astrocytic gliomas

Pilocytic astrocytoma

High-grade astrocytoma with piloid features

Pleomoprhic xanthoastrocytoma

Subependymal giant cell astrocytoma

Chordoid glioma

Astroblastoma, MN1-altered

Glioneuronal and neuronal tumors

Ganglioglioma

Gangliocytoma

Desmoplastic infantile ganglioglioma/desmoplastic infantile astrocytoma

Dysembroplastic neuroepithelial tumor

Diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters

Papillary glioneuronal tumor

Rosette-forming glioneuronal tumor

Myxoid glioneuronal tumor

Diffuse leptomeningeal glioneuronal tumor

Multinodular and vacuolating neuronal tumor

Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease)

Central neurocytoma

Extraventricular neurocytoma

Cerebellar liponeurocytoma

Ependymal tumors

Supratentorial ependymoma

Supratentorial ependymoma, ZFTA fusion-positive

Supratentorial ependymoma, YAP1 fusion-positive

Posterior fosse ependymoma

Posterior fossa group A (PFA) ependymoma

Posterior fossa group B (PFB) ependymoma

Spinal ependymoma

Spinal ependymoma, MYCN-amplified

Myxopapillary ependymoma

Subependymoma

Lymphomas

CNS lymphomas

Primary diffuse large B-cell lymphoma of the CNS

Immunodeficiency-associated CNS lymphomas

Lymphomatoid granulomatosis

Intravascular large B-cell lymphoma

Miscellaneous rare lymphomas in the CNS

MALT lymphoma of the dura

Other low-grade B-cell lymphomas of the CNS

Anaplastic large cell lymphoma (ALK+/ALK-)

T-cell and NK/T-cell lymphomas

Histiocytic tumors

Erdheim-Chester disease

Rosai-Dorfman disease

Juvenile xanthogranuloma

Langerhans cell histiocytosis

Histiocytic sarcoma

Diffuse meningeal melanocytic neoplasms

Diffuse meningeal melanocytioc neoplasms: Melanocytosis and melanomatosis

Circumscribed meningeal melanocytic neoplasms

Circumscribed meningeal melanocytic neoplasms: Melanocytoma and melanoma

Meningioma

Soft tissue tumors

Fibroblastic and myofibroblastic tumors

Solitary fibrous tumor

Vascular tumors

Hemangiomas and vascular malformations

Hemangioblastoma

Skeletal muscle tumors

Rhabdomyosarcoma

Tumors of uncertain differentiation

Intracranial mesenchymal tumor, FET::CREB fusion-positive

CIC-rearranged sarcoma

Primary intracranial sarcoma, DICER1-mutant

Ewing sarcoma

Chondro-osseous tumors

Chondrogenic tumors

Mesenchymal chondrosarcoma

Chondrosarcoma

Notochordal tumors

Chordoma

Metastases to the brain and spinal cord parenchyma

Metastases to the meninges

Pineocytoma

Pineal parenchymal tumor of intermediate differentiation

Pineoblastoma

Papillary tumor of the pineal region

Desmoplastic myxoid tumor of the pineal region, SMARCB1-mutant

Adamantinomatous craniopharyngioma

Papillary craniopharyngioma

Pituicytoma, granular cell tumor of the sellar region, and spindle cell oncocytoma

Pituitary adenoma/pituitary neuroendocrine tumor

Pituitary blastoma