Tumors with apocrine and eccrine differentiation

Benign apocrine and eccrine tumors

Hidrocystoma/cystadenoma

Syringoma

Poroma

Syringofibroadenoma

Hidradenoma

Spiradenoma

Cylindroma

Tubular adenoma

Syringocystadenoma papilliferum

Mixed tumor

Myoepithelioma

Malignant apocrine and eccrine tumors

Adnexal adenocarcinoma, NOS

Microcystic adnexal carcinoma

Cribriform tumor (previously carcinoma)

Porocarcinoma

NUT carcinoma

Malignant neoplasms arising from spiradenoma, cylindroma, or spiradenocylindroma

Malignant mixed tumor

Hidradenocarcinoma

Endocrine mucin-producing sweat gland carcinoma

Mucinous carcinoma

Digital papillary adenocarcinoma

Adenoid cystic carcinoma

Apocrine carcinoma

Squamoid ductal eccrine carcinoma

Syringocystadenocarcinoma papilliferum

Secretory carcinoma

Signet-ring cell/histiocytoid carcinoma

Tumors with follicular differentiation

Benign tumors with follicular differentiation

Trichoblastoma

Pilomatricoma

Melanocytic matricoma

Trichilemmoma

Trichoadenoma

Trichofolliculoma

Pilar sheath acanthoma

Tumor of the follicular infundibulum

Trichodiscomas and fibrofolliculomas

Malignant tumors with follicular differentiation

Proliferating trichilemmal tumor

Pilomatrical carcinoma

Trichoblastic carcinoma/carcinosarcoma

Trichilemmal carcinoma

Tumors with sebaceous differentiation

Benign tumors with sebaceous differentiation

Sebaceoma

Sebaceous adenoma

Malignant tumors with sebaceous differentiation

Sebaceous carcinoma

Site specific appendageal tumors

Benign site-specific appendageal tumors

Hidradenoma papilliferum

Fibroadenoma and phyllodes tumors of anogenital mammary-like glands

Malignant site-specific appendageal tumors

Mammary Paget disease

Extramammary Paget disease

Adenocarcinoma of mammary-gland type

Familial melanoma

BAP1 tumor predisposition syndrome

Xeroderma pigmentosum

Nevoid basal cell carcinoma syndrome (Gorlin sydrome)

Carney complex

Muir-Torre syndrome

Brooke-Spiegler and related syndromes

Carcinoma precursors and benign simulants

Premalignant keratoses and precursors

Actinic keratosis

Arsenical keratosis

PUVA keratosis

Squamous cell carcinoma in situ (Bowen disease)

Verrucae

Verruca vulgaris

Verruca plantaris and palmaris

Verruca plana

Benign acanthomas/keratoses

Seborrheic keratosis

Solar lentigo

Lichen planus-like keratosis

Clear cell acanthoma

Large cell acanthoma

Warty dyskeratoma

Other benign keratoses

Epidermal carcinomas

Basal cell carcinomas

Superficial basal cell carcinoma

Nodular basal cell carcinoma

Micronodular basal cell carcinoma

Infiltrating basal cell carcinoma

Sclerosing/morpheic basal cell carcinoma

Basosquamous carcinoma

Basal cell carcinoma with sarcomatoid differentiation

Basal cell carcinoma with adnexal differentiation

Fibroepithelial basal cell carcinoma

Keratoacanthomas

Keratoacanthoma

Squamous cell carcinomas

Verrucous squamous cell carcinoma

Acantholytic squamous cell carcinoma

Lymphoepithelial carcinoma

Clear cell squamous cell carcinoma

Spindle cell squamous cell carcinoma

Squamous cell carcinoma with sarcomatoid differentiation

Neuroendocrine neoplasms

Neuroendocrine carcinomas

Merkel cell carcinoma

Melanocytic neoplasms in intermittenly sun-exposed skin

Nevi

Junctional, compound, and dermal nevi

Simple lentigo and lentiginous melanocytic nevus

Dysplastic Nevus

Nevus spilus

Special-Site Nevi (of breast, axilla, scalp, and ear)

Halo nevus

Meyerson nevus

Recurrent Nevus

Combined Nevus

Melanocytomas

WNT-activated deep penetratin melanocytoma (nevus)

Pigmented epithelioid melanocytoma

BAP1-inactivated melanocytoma

MITF pathway-activated melanocytic tumors

Melanoma intermittently sun exposed skin

Low-CSD melanoma (including superficial spreading melanoma)

Melanocytic neoplasms in chronically sun-exposed skin 

Melanoma in Chronically Sun-Exposed Skin

Lentigo maligna melanoma

Desmoplastic melanoma

Spitz Tumors

Spitz nevi

Pigmented spindle cell nevus (Reed nevus)

Spitz nevus

Spitz melanocytoma

Spitz melanocytoma (Atypical Spitz tumor)

Spitz melanoma

Spitz melanoma

Melanocytic tumors in acral skin

Acral nevi

Acral nevus

Acral melanomas

Acral melanoma

Genital and mucosal melanocytic tumors

Mucosal and genital nevi

Melanosis

Genital nevus

Mucosal melanomas

Mucosal melanomas

Blue nevi and related tumors

Blue nevi and melanocytosis

Nevus of Ito and nevus of Ota

Congenital dermal melanocytosis

Blue nevus

Melanomas arising from blue nevi

Melanoma arising in blue nevus

Congenital melanocytic tumors

Congenital nevi

Congenital melanocytic nevus

Proliferative nodules in congenital melanocytic nevus

Melanomas arising in congenital nevi

Melanoma arising in giant congenital nevus

Ocular and CNS melanocytic tumors

Conjunctival melanocytic tumors

Conjunctival nevus

Conjunctival melanocytic intraepithelial lesions

Conjunctival melanoma

Uveal melanocytic tumors

Uveal melanocytoma

Uveal melanoma

CNS melanocytic tumors

Diffuse meningeal melanocytic neoplasms: melanocytosis and melanomatosis

Circumscribed meningeal melanocytic neoplasms: melanocytoma and melanoma

Nodular, nevoid and metastatic melanomas

Nodular and other melanomas

Nodular melanoma

Nevoid melanoma

Dermal melanoma

Metastatic melanomas

Melanoma metastatic to the skin

Melanoma metastatic to other organs

Metastases to skin

Cancer of unknown primary site

Tinea Nigra

Adipocytic tumors

Nevus lipomatosus superficialis

Lipoma

Angiolipoma

Spindle cell/pleomorphic lipoma

Atypical lipomatous tumor

Pleomorphic liposarcoma

Fibroblastic, myofibroblastic, and fibrohistiocytic tumors

Benign fibroblastic, myofibroblastic, and fibrohistiocytic neoplasms 

Fibroma of tendon sheath

Calcifying aponeurotic fibroma

Sclerotic fibroma

Nuchal-type fibroma

Gardner fibroma

Pleomorphic fibroma

Elastofibroma

Desmoplastic fibroblastoma

Fibrous papule

Fibroblastic connective tissue nevus

Fibroosseous tumor of digits

Dermatofibroma (fibrous histiocytoma)

Superficial fibromatosis

Inclusion body fibromatosis

Plexiform fibrohistiocytic tumor

Superficial acral fibromyxoma

Cutaneous myxoma (superficial angiomyxoma)

Dermatomyofibroma

Multinucleate cell angiohistiocytoma

Plaque-like CD34+ dermal fibroma

Nodular fasciitis

EWSR1::SMAD3 rearranged fibroblastic tumor

Intermediate fibroblastic, myofibroblastic, and fibrohistiocytic neoplasms

Dermatofibrosarcoma protuberans

Myxoinflammatory fibroblastic sarcoma

Malignant fibroblastic, myofibroblastic, and fibrohistiocytic neoplasms

Myxofibrosarcoma

Vascular tumors

Hemangiomas

Cherry hemangioma

Sinusoidal hemangioma

Microvenular hemangioma

Hobnail hemangioma

Glomeruloid hemangioma

Papillary hemangioma

Spindle cell hemangioma

Epithelioid hemangioma

Tufted hemangioma

Angiokeratoma

Infantile hemangioma

Congenital non-progressive hemangiomas: rapidly involuting congenital hemangioma and non-involuting congenital hemangioma

Lobular capillary hemangioma

Poikilodermatous plaque-like hemangioma

Acquired elastotic hemangioma

Verrucous venous malformation

Arteriovenous malformation

Other benign vascular tumors

Lymphangioma (superficial lymphatic malformation)

Cutaneous epithelioid angiomatous nodule

Post-radiation atypical vascular lesion

Intermediate vascular neoplasms

Pseudomyogenic hemangioendothelioma

Epithelioid hemangioendothelioma

Hobnail hemangioendothelioma

Composite hemangioendothelioma

Kaposi sarcoma

Malignant vascular sarcomas

Cutaneous angiosarcoma

Pericytic and perivascular tumors

Benign pericytic and perivascular neoplasms

Glomus tumor

Myopericytoma

Myofibroma and myofibromatosis

Angioleiomyoma

Smooth mucle tumors

Benign smooth muscle neoplasms

Smooth muscle hamartoma

Cutaneous leiomyomas

EBV-associated smooth muscle tumor

Intermediate smooth muscle neoplasms

Atypical intradermal smooth muscle neoplasm

Neural tumors

Benign neural neoplasms

Dermal hyperneury/Epithelial sheath neuroma

Solitary circumscribed neuroma

Dermal nerve sheath myxoma

Perineurioma

Neurofibroma

Schwannoma

Granular cell tumor

Hybrid nerve sheath tumors

Malignant neural neoplasms

Malignant peripheral nerve sheath tumor

Tumors of uncertain differentiation

Benign neoplasms of uncertain differentiation

Cellular neurothekeoma

Epithelioid fibrous histiocytoma

Non-neural granular cell tumor

PEComa

Intermediate neoplasms of uncertain differentiation

Angiomatoid fibrous histiocytoma

NTRK-rearranged spindle cell neoplasm

Atypical fibroxanthoma

Superficial CD34+ fibroblastic tumor

Malignant neoplasms of uncertain differentiation

Pleomorphic dermal sarcoma

Epithelioid sarcoma

CRTC1::TRIM11 cutaneous tumor

Dermal clear cell sarcoma

Ewing sarcoma

Myeloid proliferations and neoplasms

Mastocytosis

Mastocytosis

Mast cell sarcoma

Secondary cutaneous involvement in myeloid neoplasms

Cutaneous involvement in myeloid neoplasms, including myeloid sarcoma

Histiocytic or dendritic cell neoplasms

Plasmacytoid dendriticc cell neoplasms

Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm

Blastic plasmacytoid dendritic cell neoplasm

Langerhans cell neoplasms

Langerhans cell histiocytosis

Histiocytic tumors

Xanthelasma

Juvenile xanthogranuloma

Reticulohistiocytosis

Rosai-Dorfman disease

Erdheim-Chester disease

ALK positive histiocytosis

Histiocytic sarcoma

Other dendritic cell neoplasms

Indeterminate dendritic cell tumor

Cutaneous B-cell lymphoproliferative disorders and neoplasms

Reactive B-cell rich lymphoid proliferations

Primary cutaneous mature B cell neoplasms

Primary cutaneous marginal zone lymphoma

Primary cutaneous follicle center lymphoma

Primary cutaneous diffuse large B-cell lymphoma, leg type

Intravascular large B-cell lymphoma

Cutaneous involvement in primary extracutaneous B-cell lymphomas and leukemias

Mantle cell lymphoma

Burkitt lymphoma

Chronic lymphocytic leukemia/small lymphocytic lymphoma

B-lymphoblastic leukemia/lymphoma

Secondary lymphomatoid granulomatosis

Cutaneous T-cell and NK-cell lymphoproliferative disorders and neoplasms

Reactive T-cell rich lymphoid proliferations

Primary cutaneous T cell disorders

Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder

Mycosis fungoides

Primary cutaneous CD30+T-cell lymphoproliferative disorder: Lymphomatoid papulosis

Primary cutaneous CD30+ T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell carcinoma

Subcutaneous panniculitis-like T-cell lymphoma

Primary cutaneous gamma/delta T-cell lymphoma

Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder

Primary cutaneous CD8-positive aggressive epidermotrophic cytotoxic T-cell lymphoma

Primary cutaneous peripheral T-cell lymphoma, NOs

Sezary syndrome

EBV-positive lymphoproliferative diseases of childhood

Severe mosquito bite allergy

Hydroa vacciniforme lymphoproliferative disorder

Secondary cutaneous involvement in T-cell and NK-cell lymphomas and leukemias

Anaplastic large cell lymphoma

Nodal T follicular helper lymphoma, angioimmunoblastic type

T-cell prolymphocytic leukemia

T-lymphoblastic leukemia/lymphoma

Adult T cell leukemia/lymphoma

Extranodal NK/T-cell lymphoma

Other cutaneous lymphoproliferative disorders

Lymphoprolfierative disorders and lymphomas associated with immunodeficiency and dysregulation

EBV-positive mucocutaneous ulcer

Inborn error of immunity-associated lymphoproliferative disorders

Nail bed Epithelial Tumors

Onychomatricoma

Onychopapilloma

Ungual fibrokeratoma

Onychocytic matricoma

Subungual keratoacanthoma