Tumor-like lesions with B-cell predominance

Reactive B-cell rich lymphoid proliferations that can mimic lymphoma

IgG4-related disease

Unicentric Castleman disease

Idiopathic multicentric Castlemand disease

KSH/HHV8-associated multicentric Castleman disease

Precursor B cell neoplasms

B-lymphoblastic leukemias/lymphomas

B-lymphoblastic leukemia/lymphoma

B-lymphoblastic leukemia/lymphoma with high hyperdiploidy

B-lymphoblastic leukemia/lymphoma with hypodiploidy

B-lymphoblastic leukemia/lymphoma with iAMP21

B-lymphoblastic leukemia/lymphoma with BCR::ABL1 fusion

B-lymphoblastic leukemia/lymphoma with BCR::ABL1-like features

B-lymphoblastic leukemia/lymphoma with KMT2A rearrangement

B-lymphoblastic leukemia/lymphoma with ETV6::RUNX1 fusion

B-lymphoblastic leukemia/lymphoma with ETV6:RUNX1-like features

B-lymphoblastic leukemia/lymphoma with TCF3::PBX1 fusion

B-lymphoblastic leukemia/lymphoma with IGH::IL3 fusion

B-lymphoblastic leukemia/lymphoma with TCF3::HLF fusion

B-lymphoblastic leukemia/lymphoma with other defined genetic alterations

B-lymphoblastic leukemia/lymphoma NOS

Mature B-cell neoplasms

Preneoplastic and neoplastic small lymphocytic proliferations

Monoclonal B-cell lymphocytosis

Chronic lymphocytic leukemia/small lymphocytic lymphoma

Splenic B cell lymphomas and leukemias

Hairy cell leukemia

Splenic marginal zone lymphoma

Splenic diffuse red pulp small B-cell lymphoma

Splenic B-cell lymphoma/leukemia with prominent nucleoli

Lymphoplasmacytic lymphoma

Lymphoplasmacytic lymphoma

Marginal zone lymphoma

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue

Primary cutaneous marginal zone lymphoma

Nodal marginal zone lymphoma

Pediatric nodal marginal zone lymphoma

Follicular lymphoma

In situ follicular B-cell neoplasm

Follicular lymphoma

Pediatric-type follicular lymphoma

Duodenal-type follicular lymphoma

Cutaneous follicle center lymphoma

Primary cutaneous follicule center lymphoma

Mantle cell lymphoma

In situ mantle cell neoplasm

Mantle cell lymphoma

Leukemic non-nodal mantle cell lymphoma

Transformations of indolent B cell lymphomas

Transformation of indolent B cell lymphomas

Large B cell lymphomas

Diffuse large B cell lymphoma NOS

T cell/histiocyte-rich large B cell lymphoma

Diffuse large B-cell lymphoma/high grade B cell lymphoma with MYC and BCL2 rearrangements

ALK-positive large B cell lymphoma

Large B-cell lymphoma with IRF4 rearrangement

High grade B cell lymphoma with 11q aberration

Lymphomatoid granulomatosis

EBV-positive diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma assocaited with chronic inflammation

Fibrin-associated large B cell lymphoma

Fluid overload-associated large B-cell lymphoma

Plasmablastic lymphoma

Primary large B-cell lymphoma of immune-privileged sites

Primary cutaneous diffuse large B-cell lymphoma, leg type

Intravascular large B-cell lymphoma

Primary mediastinal large B-cell lymphoma

Mediastinal large B-cell lymphoma

Mediastinal grey zone lymphoma

High-grade B cell lymphoma NOS

Burkitt lymphoma

Burkitt lymphoma

KSHV/HHV8-associated B-cell lymphoid proliferations and lymphomas

Primary effusion lymphoma

KSHV/HHV8-positive diffuse large B cell lymphoma

KSH/HHV8-positive germinotropic lymphoproliferative disorder

Lymphoid proliferations and lymphomas associated with immune deficiency and dysregulation

Hyperplasias arising in immune deficiency/dysregulation

Polymorphic lymphoproliferative disorders arising in immune deficiency/dysregulation

EBV-positive mucocutaneous ulcer

Lymphomas arising in immune deficiency/dysregulation

Inborn error of immunity-associated lymphoid proliferations and lymphomas

Hodgkins lymphoma

Classic Hodgkin lymphoma

Nodular lymphocyte-predominant Hodgkin lymphoma

Plasma cell neoplasms and other diseases with paraproteins

Monoclonal gammopathies

Cold agglutinin disease

IgM monoclonal gammopathy of undetermined significance

Non-IgM monocloncal gammopathy of undetermined significance

Monoclonal gammopathy of renal significance

Diseases with monoclonal immunoglobulin deposition

Immunoglobulin-related amyloidosis (AL amyloidosis)

Monoclonal immunoglobulin deposition disease

Heavy chain diseases

Mu heavy chain disease

Gamma heavy chain disease

Alpha heavy chain disease

Plasm cell neoplasms

Plasmacytoma

Plasma cell myeloma/multiple myeloma

Plasma cell neoplasms with associated paraneoplastic syndrome

Fanconi anemia

Bloom syndrome

Ataxia-telangiectasia

RASopathies

Plasmacytoid dendritic cell neoplasms

Plasmacytoid dendritic cell neoplasms

Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm

Blastic plasmacytoid dendritic cell neoplasm

Langerhaans cell and other dendritic cell neoplasms

Langerhaans cell neoplasms

Langerhaans cell histiocytosis

Langerhaans cell sarcoma

Other dendritic cell neoplasms

Interdeterminate dendritic cell tumor

Interdigitating dendritic cell sarcoma

Histiocyte/macrophage neoplasms

Histiocytic neoplasms

Juvenile xanthogranuloma

Erdheim-Chester disease

Rosai-Dorfman disease

ALK-positive histiocytosis

Histiocytic sarcoma

Myeloid precursor lesions

Clonal hematopoiesis

Clonal hematopoiesis

Cloncal cytopenia of undetermined significance

Myeloproliferative neoplasms

Myeloproliferative neoplasms

Chronic myeloid leukemia

Chronic neutrophilic leukemia

Chronic eosinophilic leukemia

Polycythemia vera

Essential thrombocythemia

Primary myelofibrosis

Juvenile myelomonocytic leukemia

Myeloproliferative neoplasm NOS (unclassifiable)

Mastocytosis

Cutaneous mastocytosis

Systemic mastocytosis

Mast celll sarcoma

Myelodysplastic neoplasms

Myelodysplastic neoplasms with defining genetic abnormalities

Myelodysplastic neoplasm with low blasts and 5q deletion

Myelodysplastic neoplasm with low blasts and SF3B1 mutation

Myelodysplastic neoplasm with biallelic TP53 inactivation

Myelodysplastic neoplasms defined morphologically

Myelodysplastic neoplasm with low blasts

Myelodysplastic neoplasm, hypoplastic

Myelodysplastic neoplasm with increased blasts

Myelodysplastic neoplasms of childhood

Childhood myelodysplastic neoplasm with low blasts

Childhood myelodysplastic neoplasm with increased blasts

Myelodysplastic/myeloproliferative neoplasms

Chronic myelomonocytic leukemia

Myelodysplastic/myeloproliferative neoplasm with neutrophilia

Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis

Myelodysplastic/myeloproliferative neoplasm NOS

Acute myeloid leukemia

Acute myeloid leukemia with defining genetic abnormalities

Acute promyelocytic leukemia with PML::RARA fusion

AML with RUNX1::RUNX1T1 fusion

AML with CBFB::MYH11 fusion

AML with DEK::NUP214 fusion

AML with RBM15::MRTFA fusion

AML with BCR::ABL1 fusion

AML with KMT2A rearrangement

AML with MECOM rearrangement

AML with NUP98 rearrangement

AML with NPM1 mutation

AML with CEBPA mutation

AML, myelodysplastia-related

AML with other defined genetic alterations

Acute myeloid leukemia defined by differentiation

AML with minimal differentiation

AML without maturation

AML with maturation

Acute basophilic leukemia

Acute myelomonocytic leukemia

Acute monocytic leukemia

Acute erythroid leukemia

Acute megakaryoblastic leukemia

Myeloid sarcoma

Myeloid sarcoma

Secondary myeloid neoplasms

Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions

Myeloid neoplasm post cytotoxic therapy

Myeloid neoplasms associated with germline predisposition

Myeloid proliferations associated with Down syndrome

Myeloid/lymphoid neoplasms

Myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions

Myeloid/lymphoid neoplasms with PDGFRA rearrangement

Myeloid/lymphoid neoplasms with PDGFRB rearrangement

Myeloid/lymphoid neoplasms with FGFR1 rearrangement

Myeloid/lymphoid neoplasms with JAK2 rearrangement

Myeloid/lymphoid neoplasms with FLT3 rearrangement

Myeloid/lymphoid neoplasms with ETV6::ABL1 fusion

Myeloid/lymphoid neoplasms with other tyrosine kinase gene fusion

Acute leuekmias of mixed or ambiguous lineage

Acute leukemia of ambiguous lineage with defining genetic abnormalities

Mixed phenotype acute leukemia with BCR::ABL1 fusion

Mixed phenotype acute leukemia with KMT2A rearrangement

Acute leukemia of ambiguous lineage with other defined genetic alterations

Acute leukemia of ambiguous lineage defined immunophenotypically

Mixed-phenotype acute leukemia, B/myeloid

Mixed-phenotype acute leukemia, T/myeloid

Mixed-phenotype acute leukemia, rare types

Acute leukemia of ambiguous lineage NOS

Acute undifferentiated leukemia

Mesenchymal dendritic cell neoplasms

Follicular dendritic cell neoplasms

Follicular dendritic cell sarcoma

EBV-positive inflammatory follicular dendritic cell sarcoma

Fibroblastic reticular cell tumor

Myofibroblastic tumors

Myofibroblastic tumors

Intranodal palisaded myofibroblastoma

Spleen-specific vascular-stromal tumors

Splenic vascular-stromal tumors

Littoral cell angioma

Splenic hamartoma

Sclerosing angiomatoid nodular transformation of spleen

Tumor-like lesions with T-cell predominance

Kikuchi-Fujimoto disease

Autoimmune lymphoproliferative syndrome

Indolent T-lymphoblastic proliferation

Precursor T-cell neoplasms

T-lymphoblastic leukemia/lymphoma

T-lymphoblastic leukemia/lymphoma NOS

Early T-precursor lymphoblastic leukemia/lymphoma

Mature T-cell and NK-cell neoplasms

Mature T-cell and NK-cell leukemias

T-prolymphocytic leukemia

T-large granular lymphocytic leukemia

NK-large granular lymphocytic leukemia

Adult T-cell leukemia/lymphoma

Sezary syndrome

Aggressive NK-cell leukemia

Primary cutaneous T-cell lymphoid proliferations and lymphomas

Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder

Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder

Mycosis fungoides

Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis

Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma

Subcutaneous panniculitis-like T-cell lymhpoma

Primary cutaneous gamma-delta T cell lymphoma

Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma

Primary cutaneous peripheral T-cell lymphoma NOS

Intestinal T-cell and NK-cell lymphoid proliferations and lymphomas

Indolent T-cell lymphoma of the gastrointestinal tract

Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract

Enteropathy-associated T-cell lymphoma

Monomorphic epitheliotropic intestinal T-cell lymphoma

Intestinal T-cell lymphoma NOS

Hepatosplenic T-cell lymphoma

Hepatosplenic T-cell lymphoma

Anaplastic large cell lymphoma

ALK-positive anaplastic large cell lymphoma

ALK-negative anaplastic large cell lymphoma

Breast implant-associated anaplastic large cell lymphoma

Nodal T follicular helper cell lymphoma

Nodal T follicular helper cell lymphoma, angioimmunoblastic type

Nodal T follicular helper cell lymphoma, follicular type

Nodal T follicular helper cell lymphoma NOS

Other peripheral T-cell lymphomas

Peripheral T-cell lymphoma NOS

EBV-positive T-cell and NK-cell lymphomas

EBV-positive nodal T- and NK-cell lymphoma

Extranodal NK/T-cell lymphoma

EBV-positive T-cell and NK-cell lymphoid proliferations and lymphomas of childhood

Severe mosquito bite allergy

Hydroa vacciniforme lymphoproliferative disorder

Systemic chronic active EBV disease

Systemic EBV-positive T-cell lymphoma of childhood